They probably are unrelated, but since alcohol, Tylenol, and methimazole are all metabolized by the liver, if one of the above is over taxing the liver (like 12 hours of drinking), it's possible that IF Alyk's liver is having a hard time with the methimazole, the alcohol won't help matters. I remember when my liver enzymes came back 8 times the normal amount, the on call doctor asked me if I had had a lot to drink the night before. Hee hee (no, not even a drop- it was just the methimazole that suckered punched my liver). The good thing though is that the liver does regenerate very quickly. So, although I don't know if it's a great idea, you're liver will probably be okay for 1 night. I don't know- I wouldn't. You need your liver. Maybe while it's starting a new drug, it might be good to treat it a little bit carefully until you've established how your body handles the methimazole.
Homeschooling mom to 4 wonderful boys!
Diagnosed with Graves Disease after my 4th baby- March 2012
Started on 5 mg. of methimazole daily for 7 weeks
Euthyroid at the end of those 7 weeks, but had to stop methimazole as liver enzymes were 8 times normal range.
Total Thyroidectomy- 6/15/12
Started Synthroid (brand name) 100 mcg. 2nd day after surgery for 6 weeks (TSH: 6.35 & free T4 in upper range and T3 just under mid- range).
Upped Synthroid to 112 mcg. 7/27/12
Euthyroid as of 8/10/12 on 112 mcg. Synthroid (TSH .79 and free T4 in upper range).