Have any of you who have taken Methimazole been on it while having elevated ALT/AST #s?
I'm wondering b/c my Endo has kept me on the Methimazole 30mg/day even though my ALT is elevated.
In early June, when I went to the ER with tachycardia and was diagnosed with hyperthyroidism, my ALT was 109 U/L (normal <32) and my AST was 48 U/L (normal <33). At the ER I was told this was related to my diagnosis. I was then put on Propranolol and was referred to an Endo.
As some of you know, I had an Endo, who wasn't really being helpful so I changed to a new one. This old Endo put me on Methimazole 30mg/day a week after my visit to the ER. At the time my ALT/AST were: ALT 76 IU/L (normal 0-40) and my AST 29 IU/L (normal 0-40). My bilirubin was 0.4 mg/dL (normal 0-1.2). The Dr. didn't think much of my elevated ALT and so I started the Methimazole.
I changed Endos and on July 9th my new Endo told me to continue taking the Methimazole 30mg/day even though at that time my ALT was 77 U/L (normal <32). He did not order AST, bilirubin.
The ALT was obviously elevated so my question is, have you been on Methimazole even though your liver #s were elevated and was your Dr. okay with it? My next set of labs is next week and I'm trying to get ready in case the #s are still elevated. He has ordered ALT only (plus TSH, FT4 and WBC).
, the Methimazole should be discontinued if hepatic transaminase values exceed 3 times the upper limit of normal. So, in my case I'm guessing it would be if the # is > 96, since <32 is the normal. This makes me feel better because last time my ALT, as I mentioned, was 77 but I would still like to hear from you and your experiences.
Thank you in advance