Hello everyone, this is my first post to the forum. I tried doing a search but didn't find any results pertaining to my issue.
A little background, I've had anxiety all my life, have been treated for it for about 4 years now. I have been diagnosed with generalized anxiety disorder. My doctor has frequently checked my thyroid levels because of my anxiety, but things always came back normally. Until this February, when my labs came back as overactive. More labs run, my primary care physician felt it was Graves disease and referred me to an endocrinologist. Of course there was about an 8 week wait to see the specialist, and she put me on 5 mg of methimazole 3x a day.
Very soon after I started on the methimazole, my anxiety started getting much worse. Taking on a different form than I've ever dealt with before. I was/am constantly stressed, sleeping poorly, grinding my teeth in my sleep, very quick to anger, and felt like I was literally going to explode out of my skin. I had to follow back up with my PCP a month after I started the medication (still waiting to see the endocrinologist) for a separate issue, and she excitedly asked me how my anxiety was doing, expecting it to be much better. She was very confused when I told her what was going on, and re-ran my blood work to see if my thyroid levels were worse. They were all in normal ranges. Since I was only a few weeks away from seeing the specialist, she told me to continue on, and tell them what was happening.
So I meet with the endocrinologist, explain my symptoms, she tells me she doesn't think I have Graves disease, that she thinks I have a toxic nodule. So she draws more blood, and sends me for an ultrasound. Ultrasound revealed a couple nodules, one of them a decent size (2.2 cm) and looked potentially suspicious, so that was followed up with a fine needle aspiration (during which I had the most epic meltdown of my life), and came back negative for cancer. Blood work came back, and the endocrinologist said she takes it back, now she does think I have Graves, based on, I think, antibodies? But my thyroid levels were still normal, so she told me to continue on with the methimazole. I told her that I really felt the medication was doing me a disservice, at this point, it was all I could do to get up and go to work every day. I had a very active social life, and I very rarely go out anymore, as it just feels like too much to cope with, and very overwhelming. They told me I hadn't given the methimazole enough time to work, which didn't make sense to me, as this was the end of April and I had been taking it since the beginning of February. Plus my levels were now normal, so how was it not working?
They scheduled me for a follow up appointment, which was yesterday. I informed the doctor again that my anxiety is very severe, to the point I would consider it debilitating. She stated this didn't make sense as my thyroid is functioning normally, and perhaps my anxiety disorder has worsened. I told her I've been treated for the anxiety for almost four years and it has never taken on a form like I am experiencing, and the fact that this all started after I began the medication seems like too much of a coincidence. She said methimazole does not have these symptoms as a side effect, but told me to hold the medication through the weekend to see if anything changes. Can methimazole even be out of my system in that short of a time? She said there is the alternative of taking PTU, but that has the potential for liver damage, so that's not the preferred medication. She took yet more blood work to check the thyroid levels again, and I have to have the blood work and ultrasound done again in July, and if the nodules have worsened, we may be looking at surgery.
Has anyone experienced such a thing on methimazole? Am I crazy for thinking the medication could be the problem? I am at my wits end on this, like something has gotta give or I will end up in a nervous breakdown. I want my life back. And as I sit here typing this, the doctor's office just called to confirm my thyroid levels are still all normal.
Also, some personal information if that's of any relevance, I am a 29 year old female, 5'10" and 350 lbs (yes morbidly obese, and I have put on close to 50 pounds in the last year without much change in diet, which is also confusing to me since most people lose weight with Graves). Also, my name is Rachel
Nice to meet everyone, and so sorry for the lengthy post.